Pertussis clinical case definition: Time for change in developing countries?
نویسندگان
چکیده
منابع مشابه
New approaches in pertussis vaccines for developing countries
The currently available pertussis vaccines are highly efficacious. However, whole cell vaccines display some reactogenicity and acellular vaccines are less toxic, but elevated costs limit their use in developing countries. Instituto Butantan, Brasil, has developed a new technology to remove lipopolysaccharides from the whole cell vaccine using a simplified and not expensive methodology, which a...
متن کامل[The clinical definition of Parkinson's disease--time for a change?].
Ever since the seminal description by James Parkinson almost 200 years ago the clinical definition of Parkinson’s Disease (PD) is anchored on the presence of motor symptoms. The internationally most widely used UK Brain Bank Criteria require the presence of bradykinesia plus at least one additional feature of tremor, rigidity or deficient postural reflexes for a clinical diagnosis of PD. On the...
متن کاملGuidelines for clinical research in developing countries.
On the basis of a review of current clinical research conditions in developing countries, guidelines have been formulated to ensure scientific validity as well as adherence to universal ethical principles. The main recommendation is that projects should be reviewed by two Institutional Review Boards, one in the country where the Study Sponsor is based, and another in the country where the study...
متن کاملClinical microbiology in developing countries.
We review the problem of limited microbiology resources in developing countries. We then demonstrate the feasibility of a cohort-based approach to integrate microbiology, epidemiology, and clinical medicine to survey emerging infections in these countries.
متن کاملAdaptation to climate change in developing countries.
Adaptation to climate change is given increasing international attention as the confidence in climate change projections is getting higher. Developing countries have specific needs for adaptation due to high vulnerabilities, and they will in this way carry a great part of the global costs of climate change although the rising atmospheric greenhouse gas concentrations are mainly the responsibili...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2019
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0219534